A
British man with HIV hopes to become the first in the world to be cured
of the disease by using a pioneering new therapy designed to eradicate
the virus.
A team of British scientists may be on the brink of developing a cure for HIV.
Researchers recently tested their pioneering therapy on the first of 50 participants in a clinical trial, The Sunday Times reported. Early tests on the first patient, a 44-year-old British social worker, show the virus is undetectable in the man's blood.
"This is one of the first serious attempts at a full cure for HIV,"
Mark Samuels of Britain's National Institute for Health Research told
The Sunday Times, Britain's largest-selling national Sunday newspaper.
"We are exploring the real possibility of curing HIV," Samuels added. "This is a huge challenge and it's still early days, but the progress has been remarkable."
Britain's National Health Service is backing the clinical trials,
which are the result of a collaboration between the universities of
Oxford, Cambridge, Imperial College London, University College London
and King's College London.
The trial's first patient, who said he was gay but did not give his
name, said he participated in the trial to help others with the
disease.
HIV, which stands for "human immunodeficiency virus," is
mainly transmitted through sexual acts or by using infected needles. The
virus weakens a person's immune system by destroying important T-cells
that fight disease and infection.
About 36.7 million people are living with HIV worldwide, according
to the U.S. Centers for Disease Control and Prevention. Around 2.1
million new cases were added in 2015, with nearly two-thirds of new
infections occurring in Sub-Saharan Africa, the CDC reported.
If left untreated, HIV can lead to acquired immunodeficiency
syndrome (AIDS). Around 1.1 million people died from AIDS-related
illnesses last year. While antiretroviral therapies can help control
HIV's effects on people's immune system, no effective cure exists yet.
The British researchers' potential cure would mirror the effects of antiretroviral therapies in some ways.
In untreated patients, the HIV hijacks T-cells and turns them into
virus-producing spawn that infect other T-cells. Antiretroviral
therapies target and suppress this activity, but they still leave
millions of dormant, infected T-cells lying in wait throughout the body.
The new treatment would both suppress infections and kill the reservoir of dormant cells, The Sunday Times reported.
Sarah Fidler, a consultant physician and professor at Imperial
College London, said medical tests of the potentially breakthrough
therapy would continue for the next five years.
"It has worked in the laboratory and there is good evidence it will work in humans too," Fidler told the British newspaper. "But we must stress that we are still a long way from any actual therapy."
Source: YahooNews
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